Nick Bosa Cleared to Return for San Francisco 49ers in Season Opener Against Rams

The return of Bosa comes after he participated in full team practice sessions for the first time since undergoing his third anterior cruciate ligament surgery last September. Defensive coordinator Raheem Morris made it clear that the franchise has no intention of hiding Bosa's availability for the upcoming game in Australia. At the same time, offensive coordinator Klay Kubiak expressed optimism regarding George Kittle, noting that while his workload will be evaluated across the remaining practice sessions, the veteran tight end continues to look strong after being activated from the physically unable to perform list.

Star Edge Rusher Set to Feature in Season Opener Following Knee Recovery

San Francisco 49ers defensive coordinator Raheem Morris announced on Monday in Melbourne that defensive end Nick Bosa will play in Thursday's season-opening game against the Los Angeles Rams. The team expressed complete confidence in his readiness to step onto the field for the international fixture.

The 28-year-old defensive star returned to full team practice sessions last Wednesday, marking a major milestone in his rehabilitation. It was his first full practice participation since sustaining a severe right ACL injury during competition last September.

Veteran Defender Overcomes Third ACL Surgery to Rejoin Lineup

The injury sustained last September forced Bosa to undergo his third career ACL surgery, which was the second procedure performed on his right knee. Despite the lengthy recovery period, the pass rusher successfully completed his rehabilitation to make himself available for the season opener.

Selected second overall in the 2019 draft, Bosa has established himself as a dominant force with five Pro Bowl selections. Throughout his 85 career games with San Francisco, he has recorded 64.5 sacks, 168 quarterback hits, 278 tackles, two interceptions, and 13 forced fumbles.

Tight End George Kittle Progressing Toward Potential Season Opener Appearance

In addition to Bosa's confirmed availability, San Francisco tight end George Kittle is trending positively toward playing in the matchup against the Rams. Offensive coordinator Klay Kubiak praised the veteran's condition while noting that the coaching staff will monitor his progress through the week's remaining practices.

The 32-year-old tight end was activated from the physically unable to perform list on August 23 as he nears the end of his recovery timeline. His progress provides a major boost to the team's offensive plans ahead of their opening game.

Pro Bowl Tight End Completes Rehabilitation From Torn Achilles Tendon

Kittle's path back to the active roster follows a torn right Achilles tendon suffered on January 11, 2026, during a wild-card playoff victory against the Philadelphia Eagles. The severe injury required months of intense physical therapy before he was cleared for football activities.

Despite being limited to 11 regular-season games last year due to injuries, Kittle recorded 57 receptions for 628 yards and seven touchdowns. Over his career with San Francisco, the seven-time Pro Bowl selection has accumulated 595 catches for 8,008 yards and 52 touchdowns across 124 appearances.

San Francisco Roster Nears Full Strength Ahead of Australia Fixture

The impending returns of both Bosa and Kittle significantly bolster the 49ers on both sides of the ball as they prepare for the Rams. Coaching staff members have expressed confidence in the duo's ability to contribute effectively once cleared.

With two additional practice sessions remaining before Thursday's game in Melbourne, the organization will conduct final evaluations to confirm their game-day roles. The team aims to open its season at full momentum with its key leaders back on the field.